Dr Isacsson created the Clinic for Affective disorders based on his own research and leading research in the area of Affective Disorders, ADHD and Addiction.

Dr Isacsson demonstrated in his thesis in 1994 that affective disorders like depression and bipolar disorders were poorly recognized and poorly treated in Sweden. Addressing this problem would be a key link to reducing suicide in Sweden. Besides the education of the public and primary care physicians, it was crucial to improve the quality of care at the psychiatric units.

Therefore, he became responsible in 1995 to create a specialized outpatient clinic for patients with severe affective disorders, which he then headed until 2007. His vision for the clinic was that the patients should be assured the possibility to benefit from the results of frontline psychiatric research. This required the development of a fully integrated care with sophisticated pharmacotherapy as well as psycho-pedagogical interventions of the patients families, social support, occupational therapy, and cognitive-behavioural (psycho-)therapies.

About 800 bipolar patients are continuously monitored at the clinic. Bipolar patients have, however, frequently also additional co-morbid disorders, foremost Substance Use Disorders and Attention Deficit-Hyperactivity Disorders (ADHD). It was important to simultaneously treat all the disorders in order to successfully treating any of them. Thus advanced skills also in the diagnosis and treatment of ADHD were developed as well as close collaboration with specialized units for the treatment of addiction.

The Clinic became very successful and has grown to be a department with one outpatient unit, one unit for electro-convulsive therapy (ECT), and one specialized in-patient ward. The Clinic is recognized as having the leading expertise on affective disorders in Sweden and collaborates with leading international centres. The Swedish Society for Bipolar Disorders was founded as an instrument for spreading the experiences in Sweden and for the interaction with international experts.

Dr Isacssson has more than 40 original scientific publications in leading international journals.

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